Modification of Pyrrolo[2,1-a]isoquinolines via Dicarbonylation with Dimethyl Sulfoxide and Arylacyl Bromides Affording 1,2-Dicarbonylated Pyrrolo[2,1-a]isoquinolines

Abstract A series of pyrroloisoquinolines have been modified via dicarbonylation with DMSO and arylacyl bromides. Highly functionalized 1,2-diketones bearing privileged frameworks can be prepared in acceptable to good yields (12-73%).