Reproducibility of activation in Broca's area during covert generation of single words at high field: a single trial FMRI study at 4 T.

Abstract Although functional magnetic resonance imaging (FMRI) has arguably become the most ubiquitously used imaging modality, questions remain about the reproducibility of the observed patterns of activation and the acquisition time required to achieve statistically significant and reproducible maps. In the current study, we investigated the reliability of activation in Broca's area, on both a voxel-wise and region of interest level, in response to the covert generation of a single word at 4 T. We also assessed the effects of different parametric ( P P P