Synergistic Inhibition of SARS-CoV-2 Replication Using Disulfiram/Ebselen and Remdesivir

Ting Chen,Cheng-Yin Fei,Yi Ping Chen,Karen Sargsyan,Chun-Ping Chang,Hanna S. Yuan,Carmay Lim

Synergistic Inhibition of SARS-CoV-2 Replication Using Disulfiram/Ebselen and Remdesivir

2021

Ting Chen
Cheng-Yin Fei
Yi Ping Chen
Karen Sargsyan
Chun-Ping Chang
Hanna S. Yuan
Carmay Lim

The SARS-CoV-2 replication and transcription complex (RTC) comprising nonstructural protein (nsp) 2–16 plays crucial roles in viral replication, reducing the efficacy of broad-spectrum nucleoside a...

Keywords:

Viral replication
severe acute respiratory syndrome coronavirus 2
Virology
Biology
Transcription preinitiation complex
Disulfiram
Ebselen
Nucleoside
replication
Coronavirus disease 2019

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