Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice

Jun Wang,Georgia E. Hodes,Hongxing Zhang,Song Zhang,Wei Zhao,Sam A. Golden,Weina Bi,Caroline Ménard,Veronika Kana,Marylene Leboeuf,Marc Xie,Dana Bregman,Madeline L. Pfau,Meghan E. Flanigan,Adelaida Esteban Fernández,Shrishailam Yemul,Ali Sharma,Lap Ho,Richard A. Dixon,Miriam Merad,Ming-Hu Han,Scott J. Russo,Giulio Maria Pasinetti

Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice

2018

This article uses high-throughput screening to identify two phytochemicals that are effective in promoting resilience against stress by moduling brain synaptic plasticity and peripheral inflammation.

Keywords:

Genetics
Plasticity
Cell biology
Psychological resilience
Inflammation
Synaptic plasticity
Neuroimmunology
Biology
Epigenetics
Interleukin 6
Neuroscience
Neuroplasticity

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