Long-term Dietary Restriction can Decrease the Alveolar Macrophages to Produce Reactive Oxygen Intermediates and Reactive Nitrogen Intermediates

Ａｌｖｅｏｌａｒｍａｃｒｏｐｈａｇｅｓ(ＡＭ)ｐｌａｙａｎｉｍｐｏｒｔａｎｔｒｏｌｅｉｎｔｈｅｌｕｎｇｄｅｆｅｎｓｅａｇａｉｎｓｔｉｎｆｅｃｔｉｏｎｓ .ＡｍｏｎｇｔｈｅｎｕｍｅｒｏｕｓｓｅｃｒｅｔａｒｙｐｒｏｄｕｃｔｓｏｆＡＭ ,ｔｈｅｒｅａｒｅｔｗｏｇｒｏｕｐｓｏｆｉｎｏｒｇａｎｉｃｃｏｍｐｏｕｎｄｓｗｉｔｈａｈｉｇｈｄｅｇｒｅｅｏｆｃｈｅｍｉｃａｌｒｅａｃｔｉｖｉｔｙ :ｔｈｅｒｅ ａｃｔｉｖｅｏｘｙｇｅｎｉｎｔｅｒｍｅｄｉａｔｅｓ(ＲＯＩ)ａｎｄｒｅａｃｔｉｖｅｎｉｔｒｏｇｅｎｉｎ ｔｅｒｍｅｄｉａｔｅｓ(ＲＮＩ) .Ｉｎｔｈｉｓｗｏｒｋ ,ｗｅｓｔｕｄｉｅｄｔｈｅｅｆｆｅｃｔｓｏｆｐ