Inhibitory effects and specificity of synthetic sialyldendrimers toward recombinant human cytosolic sialidase 2 (NEU2)

M Motiur Rahman2, Satoshi Kitao2, Daisuke Tsuji2,3, Kaori Suzuki4, Jun-Ichi Sakamoto4, Koji Matsuoka4, Fumiko Matsuzawa5, Sei-Ichi Aikawa5, and Kohji Itoh1,2,3 Department of Medicinal Biotechnology, Institute for Medicinal Research, Graduate School of Pharmaceutical Sciences, The University of Tokushima, Tokushima 770-8505, Japan; Agri-health Translational Research Project (No. 5130) of the Ministry of Agriculture, Forestry and Fisheries of Japan, Tokyo 108-8950, Japan; Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan; and Tokyo R&D Center, Altif Laboratories, Inc., Tokyo 135-0064, Japan