Tumor anorexia: effects on neuropeptide Y and monoamines in paraventricular nucleus

Abstract Paraventricular (PVN) concentrations of neuropeptide Y (NPY), serotonin (5-HT) and dopamine (DA) in anorectic tumor-bearing (TB) rats were measured before and after tumor resection. At onset of anorexia in TB versus non-tumor bearing (NTB) Controls 5-HT increased from 12.19±0.49 pg/μg to 14.89±0.81 pg/μg ( P P