Chemical constituents of Abies nukiangensis

Abstract During a survey on chemical constituents of Abies nukiangensis , seven previously unreported compounds, including six triterpenes ( 1 – 6 ) and one phenol ( 7 ) were isolated and characterized, together with 37 known miscellaneous chemical constituents. The structures of compounds 1 – 7 were established mainly by extensive analysis of the 1D and 2D NMR, as well as HRMS data. The absolute configurations of compounds 1 and 8 were confirmed unambiguously by the Cu-Kα X-ray crystallography. Compounds 3 and 8 – 10 showed significant anti-hepatitis C virus effects with EC 50 values of 3.73, 2.67, 1.33 and 2.25 μM, respectively.