CLOSED-LOOP CARDIOVASCULAR SYSTEM MODEL AND PARTIAL HEPATECTOMY SIMULATION

The present work aims at developing a mathematical model in order to reproduce hemodynamics changes due to liver surgeries. First, a 0D closed-loop model is developed, to simulate hepatectomy and compute post-operative average values. Due to the closed loop, the surgery impact both on and from the whole circulation can be captured, including bleeding and infusion. Then, a one-dimensional artery model is implemented to improve the closed-loop model and simulate better the changes in arterial waveforms due to surgery.