Bayesian method to predict individual SNP genotypes from gene expression data
2012
Eric Schadt and colleagues report a Bayesian method to predict individual SNP genotypes based on RNA expression data. Using simulations and empirical data sets, they show that it is possible to infer a genotypic barcode specific to an individual, although the identification of an individual as a participant in a study is limited by factors such as the availability of large-scale expression quantitative trait loci (eQTLs) and expression data sets.
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