Experimental Studies on the Anti-inflammatory Activities of Ethanol Extract of Hemistepta lyrata Bunge.

Objective To study the anti-inflammatory activities of the ethanol extract of Hemistepta lyrata Bunge.Methods The methods of xylene-induced ear edema in mice,granuloma induced with cotton ball in rats and hind paw edema induced with crystallite sodium urate in rats were used to observe the anti-inflammatory effects.The content of PGE2 was measured in hind paw edema induced with formaldehyde in mice.Results The ethanol extract of H.lyrata Bunge.could inhibit xylene-induced ear edema,granuloma induced with cotton ball and hind paw edema induced with crystallite sodium urate in rats,decrease the content of PGE2.Conclusion The ethanol extract of H.lyrata Bunge.has significant anti-inflammatory effects,which was related to its inhibitory effects on PGE2.