Andamiajes tridimensionales tipo esponjas basados en bioconjugados colágeno-quitosano como potencial biomaterial para aplicaciones en ingeniería de tejidos

We isolated chitosan from native shrimp waste streams and collagen from tilapia skin waste; composite materials were successfully obtained by mixing chitosan with collagen (80:20 v/v). Chitosan-collagen composites were formulated as a 3D sponge-like scaffold, applying previously developed methodologies involving solvent casting and freeze drying. Chitosan-collagen 3D scaffolds were characterized according to its thermal behavior (TG) and morphology (SEM). Finally, we study the effect of the addition of a porogenic agent on the water absorption capacity and morphology of the 3D scaffolds.