Ethical issues of clinical research on sudden infectious diseases and countermeasures

In December 2019, a new type of Corona Virus Disease 2019 (COVID-19) broke out and rapidly spreaded all over the world Up to now, there is no proven effective antiviral treatment In an overall climate of scientific uncertainty, social and institutional chaos, fear and mistrust, clinical research of COVID-19 face numerous challenges of ethical issues This paper takes COVID-19 as an example to discuss the ethical problems and countermeasures of clinical research on outbreaking infectious diseases, such as the challenge to the traditional ethical review way, balancing the conflict between treating patients as a doctor under the outbreak and participating in clinical study as a researcher, informed consent of subjects, and additional study risk It was proposed that even in an outbreak of infectious disease, we also need to follow common clinical research regulations and ethical norms, manage the problems brought by the outbreak, protect the safety of subjects, ensure the smooth conduct of clinical research, and promote the development of medical science