S19-3. Evaluation of rehabilitation technics using sensory-evoked and motor-related magnetic fields

To evaluate rehabilitation effects from the cortical responses has great significance. We have been studied the effects of motor, somatosensory, and auditory functions using magnetoencephalography (MEG). To evaluate rehabilitation effects from the cortical responses has great significance. We have been studied the effects of motor, somatosensory, and auditory functions using magnetoencephalography (MEG). (1) We recorded motor-evoked field for a mild hemiplegic patient. The response in the lesional hemisphere was elicited clearer by bilateral movements than by unilateral movements. These results indicate the interhemispheric balance may be controlled by bilateral movements. (2) By using somatosensory-evoked magnetic fields following noxious intraepidermal electrical stimulation (pain-SEFs), we evaluated the analgesic effect of transcranial direct current stimulation (tDCS) over the opercular somatosensory region (OP), which plays an indispensable role in pain perception. As a result, the intervention significantly decreased OP activity associated with pain-SEFs. (3) Mismatch negativity (MMN) of auditory stimuli is measured to know the automatic detection of changes. In the case of hearing-impaired participants, marked MMN was elicited when the sounds were presented by an intelligible hearing loudspeaker. The findings suggest that improving sound intelligibility may be a supportive and rehabilitative approach for hearing-impaired patients. The importance of evaluating the rehabilitation effect using brain mapping technics will increase. MEG can be one of the useful tools for evaluating rehabilitation because it has the advantage of spatiotemporal resolution.