Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland ( n =19 762), UK Biobank ( n =24 048) and the English Longitudinal Study of Ageing ( n =5766)

Ella Wigmore,T-K Clarke,David M. Howard,Mark J. Adams,Lynsey S. Hall,Yanni Zeng,Jude Gibson,Gary Davies,Ana Maria Fernandez-Pujals,P. A. Thomson,Caroline Hayward,Blair H. Smith,Lynne J. Hocking,Sandosh Padmanabhan,Ian J. Deary,David J. Porteous,Kristin K. Nicodemus,Andrew M. McIntosh

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland ( n =19 762), UK Biobank ( n =24 048) and the English Longitudinal Study of Ageing ( n =5766)

2017

Ella Wigmore
T-K Clarke
David M. Howard
Mark J. Adams
Lynsey S. Hall
Yanni Zeng
Jude Gibson
Gary Davies
Ana Maria Fernandez-Pujals
P. A. Thomson
Caroline Hayward
Blair H. Smith
Lynne J. Hocking
Sandosh Padmanabhan
Ian J. Deary
David J. Porteous
Kristin K. Nicodemus
Andrew M. McIntosh

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland ( n =19 762), UK Biobank ( n =24 048) and the English Longitudinal Study of Ageing ( n =5766)

Keywords:

Biobank
Psychiatry
Psychology
Ageing
Major depressive disorder
Genetic correlation
Brain size
Genetic architecture
Longitudinal study
Heritability
Internal medicine
Linkage disequilibrium
Multiple comparisons problem
Oncology

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