Synthesis of chromeno[2,3-c]pyrrol-9(2H)-ones by domino reactions of amino acids with ynones

The synthesis of novel chromeno[2,3-c]pyrrol-9(2H)-ones via domino reaction of amino acids with aromatic α,β-ynones is described. Obtained chromeno[2,3-c]pyrrol-9(2H)-ones possess phosphatase inhibitory activity.