Comparison of surface micro-structured and plasmonic all-fiber delivery probes for laser-induced thermotherapy of tumor cells
2016
The paper compares two different approaches to design an innovative probe with optimized heated area for
laser ablation of solid tumors: micro-patterning of the fiber delivery tip, and exploitation of the dissipation
of plasmonic waves at the metal-dielectric interface. Both probes integrate a fiber Bragg grating for real-
time monitoring of the obtained temperature increase to provide feedback to surgeons in practical applications.
Experimental characterizations carried out using liver phantoms and ex-vivo porcine livers have demonstrated
that both approaches can be used for the devised application, although further optimizations and tests are still
necessary before clinical assessment.
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