ICEHpsaHPS7, a novel multiple drug-resistance integrative conjugative element in Glaesserella parasuis.

Integrative conjugative elements (ICEs), a kind of novel self-transmissible mobile genetic element. In this study, a novel ICE was identified in Glaesserella (Haemophilus) parasuis We confirmed that it could mediate the migration of antimicrobial resistance genes in G. parasuis and found that there may have been a transferring potential between different serovar strains of G. parasuis These findings demonstrate that ICE is crucial to the horizontal transfer of antimicrobial resistance among G. parasuis.