The Synergy of Endotoxin and (1→3)-β-D-Glucan, from Gut Translocation, Worsens Sepsis Severity in a Lupus Model of Fc Gamma Receptor IIb-Deficient Mice

Jiraphorn Issara-Amphorn,Saowapha Surawut,Navaporn Worasilchai,Arthid Thim-uam,Malcolm Finkelman,Ariya Chindamporn,Tanapat Palaga,Nattiya Hirankarn,Prapaporn Pisitkun,Asada Leelahavanichkul

The Synergy of Endotoxin and (1→3)-β-D-Glucan, from Gut Translocation, Worsens Sepsis Severity in a Lupus Model of Fc Gamma Receptor IIb-Deficient Mice

2018

Jiraphorn Issara-Amphorn
Saowapha Surawut
Navaporn Worasilchai
Arthid Thim-uam
Malcolm Finkelman
Ariya Chindamporn
Tanapat Palaga
Nattiya Hirankarn
Prapaporn Pisitkun
Asada Leelahavanichkul

We investigated the influence of spontaneous gut leakage upon polymicrobial sepsis in a lupus model with Fc gamma receptor IIb-deficient (FcGRIIb-/-) mice aged 8 and 40 weeks, as representing asymptom

Keywords:

Immunology
Microbiology
Fc-Gamma Receptor
Sepsis
Systemic lupus erythematosus
Glucan
Fc gamma receptor IIB
Chromosomal translocation
Biology
Endocrinology
Lupus nephritis
Internal medicine
Asymptomatic
Cytokine
1 3 β d glucan

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