Control of type III protein secretion using a minimal genetic system

Miryoung Song,David J. Sukovich,Luciano Ciccarelli,Julia Mayr,Jesus Fernandez-Rodriguez,Ethan A Mirsky,Alex C. Tucker,D. Benjamin Gordon,Thomas C. Marlovits,Christopher A. Voigt

Control of type III protein secretion using a minimal genetic system

2017

Miryoung Song
David J. Sukovich
Luciano Ciccarelli
Julia Mayr
Jesus Fernandez-Rodriguez
Ethan A Mirsky
Alex C. Tucker
D. Benjamin Gordon
Thomas C. Marlovits
Christopher A. Voigt

The type III secretion system is a needle-like molecular machine under tight regulatory control. Here the authors construct a synthetic type III secretion system gene cluster by deconstructing and rebuilding the wild-type Salmonella pathogenicity island 1.

Keywords:

Iii protein
Pathogenicity island
Genetics
Molecular machine
Salmonella
Secretion
Gene cluster
Type three secretion system
Biology
Regulation of gene expression
Operon
Salmonella enterica

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