Sodium alginate-sodium carboxymethylcellulose-chitosan wound dressing and preparation method thereof

2014 
The invention discloses a sodium alginate-sodium carboxymethylcellulose-chitosan wound dressing and a preparation method thereof, and relates to a dressing for human body skin wounds. The wound dressing is composed of 1%-1.4% of sodium alginate, 0.6%-1% of sodium carboxymethylcellulose, 0.3%-0.9% of chitosan, 6%-8% of glycerol and the balance of water. The preparation method comprises the following steps: adding sodium alginate and sodium carboxymethylcellulose into water, adding chitosan and acetic acid so as to obtain a uniform solution, and then pouring the uniform solution into a culture dish to perform first freeze drying; then putting the dried material into a CaCl2 solution and an NaOH solution in sequence to soak, performing second freeze drying, soaking in a glycerol aqueous solution, and performing a third freeze drying so as to obtain the product. The preparation technology is simple, the cost is low, the safety and the biocompatibility are better, the characteristics of being high in absorbability, capable of maintaining moist wound condition, low in adhesion, easy to replace and the like are achieved, and wound healing is facilitated.
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