8-amido-bearing pseudomycin B (PSB) analogue: novel antifungal agents
2001
Abstract During the course of a structure–activity relationship (SAR) study on novel depsinonapeptide pseudomycin B, we synthesized a total of 12 8-amidopseudomycin analogues via standard two-step sequence from either ZPSB 2 or AllocPSB 3 . A number of these amides exhibited good in vitro antifungal activities.
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