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Guidelines for Clinical Trials

2021 
During the last decade, the evidence-based treatment of headaches has gained important advances. Several guidelines to perform research in this field have been published. The specificity, innovative mode of administration, and excellent safety profile of monoclonal antibodies acting on the CGRP or its receptor has several implications for present and future clinical trials. In this Chapter, we will discuss the aspects of patient selection, operating procedures, and outcome assessment that are mostly relevant for trials of monoclonal antibodies acting on the CGRP pathway.
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