Mechanosensitivity of vessel myocytes: role in formation of myogenic reactions

We analyze the hypothesis for existence of two independent factors, realizing of contractile properties of blood vessels in response to transmural pressure changes. The factors are a degree of vascular wall stretch and its circumferential tension. We suggest the method for qualitative and quantitative evaluation of the sensitivity of the active component of the vascular wall tension to these factors. The method favors a sophisticated understanding of mechanic regulation of vessels and hemodynamics.