Potentiometric Studies on The Complexes of Cu(II), Cd(II), Co(II), Ni(II), Pb(II) and Zn(II) With Gabapentin

Potentiometric studies have been carried out on complexes of gabapentin (chemically 2-[1-(aminomethyl)cyclohexyl]ethanoic acid ) with Cu(II), Cd(II), Co(II), Ni(II), Pb(II) and Zn(II) in 50% v/v dioxane-water medium at three different temperatures (35, 45and 55 o C) and ionic strength 0.1 mol L -1 (KNO 3 ). Calvin-Bjerrum pH titration technique as used by Irving and Rossotti has been applied to determine stability constants of the complexes. Free energy, enthalpy and entropy changes have also been evaluated.