Human Metapneumovirus Infection in a Hematopoietic Stem Cell Transplant Recipient with Relapsed Multiple Myeloma and Rapidly Progressing Lung Cancer

Human metapneumovirus (HMPV) was isolated from a 63-year-old multiple myeloma patient who had undergone hematopoietic stem cell transplantation and who presented with lower respiratory tract infection several weeks prior to the diagnosis of lung cancer. The isolate was phylogenetically and biologically characterized and compared to HMPV prototypes and recent pediatric isolates. Remarkably, it belonged to the novel genomic subgroup A2b.