Laxanol, a new 2,5-diaryl-3,4-dihydroxymethyltetrahydrofuran type lignan from Justicia laxa

The unsymmetrical 2,5-diaryl-tetrahydrofuran type lignan, 2-(3'-methoxy-4'-hydroxyphenyl)-3,4-dihydroxymethyl-5-(3"-methoxy-5"-hydroxyphenyl)-tetrahydrofuran, laxanol (1), was obtained from Justicia laxa via high-throughput natural product chemistry methods as a mass-limited sample and its structure was elucidated by capillary scale NMR and HR-/LR-ESIMS analyses.