Gas-chromatography–mass spectrometry analysis of dimethyl fumarate in consumer products

Abstract Two methods for the analysis of dimethyl fumarate (DMF) on silica gel, leather and other similar products are presented. The methods are based on solvent extraction or head space solid phase microextraction coupled with gas-chromatography–mass spectrometry. The methods are developed in order to satisfy the mandatory requirements of the European Community and with the aim to have easy and reliable methods to provide rapid responses.