Influence of phospholipid composition on cationic emulsions/DNA complexes: physicochemical properties, cytotoxicity, and transfection on Hep G2 cells

Michelle Fraga,Fernanda Bruxel,Valeska Lizzi Lagranha,Helder Ferreira Teixeira,Ursula da Silveira Matte

Influence of phospholipid composition on cationic emulsions/DNA complexes: physicochemical properties, cytotoxicity, and transfection on Hep G2 cells

2011

Michelle Fraga
Fernanda Bruxel
Valeska Lizzi Lagranha
Helder Ferreira Teixeira
Ursula da Silveira Matte

Background Cationic nanoemulsions have been recently considered as potential delivery systems for nucleic acids. This study reports the influence of phospholipids on the properties of cationic nanoemulsions/DNA plasmid complexes.

Keywords:

Materials science
Biochemistry
Cationic polymerization
Phospholipid
Molecular biology
Transfection
DNA
Drug carrier
Hep G2
Nucleic acid
Cytotoxicity
Plasmid

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