Whole blood RNA-Seq analysis of stocker calves reveals insights into BRD

Bovine respiratory disease (BRD) is the leading cause of morbidity and mortality in stocker cattle. It is difficult to predict which cattle will develop BRD. Improved prediction could facilitate more responsible and rational use of antimicrobials and vaccines to limit BRD. We hypothesize that altered transcriptional profiles in the blood of stocker calves on arrival represent regulatory pathways including biomarkers useful to improve prediction of BRD risk.