anxiolytic agents with reduced sedative side effects and ataxic.

Compound of formula I or a salt or prodrug thereof, (see formula) wherein: Y and Z are taken together with the two carbon atoms involved to form a ring selected from phenyl and thienyl, which ring is substituted on the C (8) with at least the substituent -C = CR, wherein R is H, Si (CH3) 3, t-butyl, isopropyl, methyl or cyclopropyl; R2 is a cyclic ring or a 5- or 6-membered substituted or unsubstituted at least partially unsaturated, wherein if substituted the substituent is one or more of F, Cl, Br or NO2 at the 2 ''; and R10 is (See formula) wherein n is 0 to 4, (See formula) wherein n is 1 or 2, in which (see formula) Y '' and Z '' are taken together with the two carbon atoms involved to form a ring selected from phenyl and thienyl, which ring is substituted at the C (8) '' with at least the substituent -C = CR, where R '' H, Si (CH3) 3, t-butyl, isopropyl, methyl or cyclopropyl; R5 is a halogenated or unhalogenated C1 to C4 branched or straight chain or methyl-cyclopropyl alkyl; R6 is a C1 to C4 branched or straight chain or methyl-cyclopropyl; R1 'is one of H, CH3, CF3, CH2CF3, CH2CH3, or cyclopropyl; R2 'is a cyclic or heterocyclic ring of 5 or 6 substituted or unsubstituted links at least partially unsaturated, wherein if the substituent is substituted is one or more of F, Cl, Br or NO2 at the 2' ' ; and wherein when R10 is C-CO2-R5, R1 is one of H, CH3, CF3, CH2CF3, CH2CH3, CH2C = CH, an alkyl or cyclopropyl; but, R1 is one of H, CH3, CF3, CH2CH3, CH2CF3, or cyclopropyl; and wherein (See formula) when R10 is (See formula) B is O or NH and wherein -BCH2B- is optionally substituted with -N (R7) -N (R7), wherein R7 is one of from H, CH3, alkyl or cycloalkyl; and when R10 is (See formula) B is O, NH or -N (R7) -N (R7) -, wherein R7 is one of H, CH3, alkyl or cycloalkyl.