Site-specific synthesis of 3-Se-1,2-unsaturated glycosides with R-Se-Se-R as the nucleophile precursors promoted by InCl3/Hf(OTf)4

Abstract By using Hf(OTf)4 as the catalyst, a series of 3-Se 1,2-unsaturated glucosides have been synthesized site-specifically from tri-O-acetyl- d -glucal, 3,4-di-O-acetyl- l -rhamnal or 2,4,6-tri-O-benzyl- d -glucal with alkyl(aryl) hydroselenides as the nucleophile precursors in good yield.