Systematic review and meta-analysis of association between cognitive tests and on-road driving ability in people with dementia

ABSTRACTObjectives: To assess the strength of association between cognitive tests and on-road driving ability in people with dementia by conducting a systematic review and meta-analysis. Methods: A literature search strategy was developed using terms related to dementia and driving. Fifteen databases were searched. Studies were selected if they investigated the predictive ability of cognitive tests and on-road fitness to drive in people with dementia. The primary author performed the initial screening of title and abstract of each paper. Two reviewers then independently checked whether the abstracts met the inclusion and exclusion criteria. The primary author also hand searched included studies, reference lists and conducted citation searches. Studies were quality assessed using Newcastle-Ottawa Quality Assessment Scale for Cohort and Case–Control Studies. A random effect model was employed to analyse effect size. Results: The initial search identified 6734 articles, of which 47 full-text articles were sc...