Biodegradable Polymer with Effective Near-Infrared-II Absorption as Photothermal Agent for Deep Tumor Therapy.

Photothermal therapy holds great promise for cancer treatment due to its effective tumor ablation and minimal invasiveness. We report herein a new class of biodegradable photothermal agents with effective adsorption in both Near-Infrared-I and II windows for deep tumor therapy. As demonstrated in a deep-seated ovarian cancer model, photothermal therapy using 1064 nm irradiation effectively inhibits tumor progression and prolongs survival spans. This work provides a new design of photothermal agents towards a more effective therapy of tumors. This article is protected by copyright. All rights reserved.