Determination of bronopol in cosmetic products by HPLC with electrochemical detection.
2001
A procedure is described for the assay of bronopol in cosmetics by HPLC coupled with constant-potential amperometric detection. Samples were analysed on an Alltima C 18 column with methanol-phosphate buffer as the eluent and detected at a porous graphite electrode set at a reduction potential of -0.9 V. The recovery of bronopol from different cosmetic matrices was between 96.4 and 98.8% and the precision of the method was better than 4.5% relative standard deviation.
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