Short-term effects of extremely low frequency electromagnetic fields exposure on Alzheimer's disease in rats.

AbstractPurpose: With the development and widespread use of electromagnetic field (EMF) technology, recent studies are focusing on the effects of EMF on human health. Recently, extremely low frequency electromagnetic fields (ELF-EMF) have been studied with great interest due to their possible effects on Alzheimer's disease (AD). The objective of the present study was to investigate the interaction between ELF-EMF exposure and memory impairment in rats.Materials and methods: Twenty healthy male Sprague Dawley (SD) rats were randomly divided into two groups (n = 10). Animals were exposed to 100 μT/50 Hz ELF-EMF or subjected to sham exposure when 12 weeks old. After 12 weeks, the Morris water maze (MWM) was used to test the changes in cognitive and memory ability. Amyloid-beta (Aβ) content in cortex, hippocampus and plasma were measured by ELISA assays. The morphology of neuron was detected by H&E staining.Results: After exposure, the body weight of rats showed no difference compared with the control group. ...