RADIATION CANCER: CANCER CAUSED BY IRRADIATION OF NON-MALIGNANT DISEASES OF THE NECK AND PHARYNX

1961 
A statistical analysis was made of 15 cases of so-called radiation cancer of the neck, which occurred following the irradiation of non-cancerous diseases (14 cases of tuberculosis of the lymph nodes and one hemangioma). The cancers which developed were 14 cases of squamous and one of adenocarcinoma. Although it was not confirmed that previous irradiations were the carcinogenic cause, the following characteristics were observed: after previous irradiation a relatively longer time (18--35 years) elapsed before the development of cancer. The irradiation dosage seemed to be more than several thousand roentgens, because the scar of skin induced by previous irradiations was clearly marked. The patients were generally younger than those with a spontaneously developed cancer. The lesions were already damaged by previous irradiation, resulting in atrophy, desiccation, pigmentation of the skin, and capillary dilatation. The prognosis was poor in all patients. (Abstr. Japan Med., 2: No. 6, June 1962).
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