Repetitive transcranial magnetic stimulation in non-treatment-resistant depression

Repetitive transcranial magnetic stimulation (rTMS) has been investigated as treatment for major depressive episodes since the early 1990s. Using data from a recent meta-analysis, we show that most patients included in randomised trials display relatively high degrees of treatment resistance. This might have unfavourably biased the clinical reputation of rTMS. Declaration of interests M.K. has received a lecture fee from Innomed Medizintechnik in 2017 and 2018.