A spatiotemporal microenvironment model to improve design of a 3D bioreactor for red cell production

Mark C. Allenby,Naoki Okutsu,Kate Brailey,Joana Guasch,Qiming Zhang,Nicki Panoskaltsis,Athanasios Mantalaris

A spatiotemporal microenvironment model to improve design of a 3D bioreactor for red cell production

2021

Mark C. Allenby
Naoki Okutsu
Kate Brailey
Joana Guasch
Qiming Zhang
Nicki Panoskaltsis
Athanasios Mantalaris

Cellular microenvironments provide stimuli, including paracrine and autocrine growth factors and physicochemical cues, which support efficient in vivo cell production unmatched by current in vitro ...

Keywords:

Cell
Bioreactor
Autocrine signalling
Red Cell
Chemistry
Cell biology
In vivo
Paracrine signalling
Cell therapy

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