Modulators of the complement pathway and uses thereof

A compound represented by Formula (V) or (VI): ** ** Formula wherein: Z2 is CR2 or N; R2 is hydrogen, C1-C4 alkyl or halogen; R3 is hydrogen, C1-C4 alkyl or pirimidinilmetoxi; R5 is methyl or amino; and R10 is C1-C4 alkyl, C3-C6-methyl, or halo-C1-C2.