Genome-Wide STAT3 Binding Analysis after Histone Deacetylase Inhibition Reveals Novel Target Genes in Dendritic Cells

Yaping Sun,Matthew Iyer,Richard C. McEachin,Meng Zhao,Yi Mi Wu,Xuhong Cao,Katherine Oravecz-Wilson,Cynthia Zajac,Nathan Mathewson,Shin-Rong Julia Wu,Corinne Rossi,Tomomi Toubai,Zhaohui S. Qin,Arul M. Chinnaiyan,Pavan Reddy

Genome-Wide STAT3 Binding Analysis after Histone Deacetylase Inhibition Reveals Novel Target Genes in Dendritic Cells

2017

Yaping Sun
Matthew Iyer
Richard C. McEachin
Meng Zhao
Yi Mi Wu
Xuhong Cao
Katherine Oravecz-Wilson
Cynthia Zajac
Nathan Mathewson
Shin-Rong Julia Wu
Corinne Rossi
Tomomi Toubai
Zhaohui S. Qin
Arul M. Chinnaiyan
Pavan Reddy

STAT3 is a master transcriptional regulator that plays an important role in the induction of both immune activation and immune tolerance in dendritic cells (DCs). The transcriptional targets of STAT3

Keywords:

SAP30
HDAC11
HDAC4
HDAC10
Histone deacetylase 5
Dendritic cell
Biology
Immune tolerance
Histone deacetylase 2
Molecular biology
Cancer research
Regulation of gene expression
Histone deacetylase

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