Anti-inflammatory effects of the phosphodiesterase 4 inhibitor cilomilast (Ariflo) in COPD

An enclosure for telecommunications equipment has a base and a lid pivotally connected to the base. The enclosure has an aperture defined by aperture edges through which one or more wires can be fed. A first elastically deformable insert is attached to a mounting surface on the base and a second elastically deformable insert is attached to a mounting surface on the lid, both adjacent to the aperture, such that when the lid is closed, the first and second inserts deform under contact with each other and with any wires fed through the aperture to reduce the size of gaps between the wires and the aperture edges. In one embodiment, the inserts have slots that enable non-continuous deformations to provide better sealing characteristics.