Effects of Environmental Pollution on Changes in Blood Biochemical Parameters

Abstract   A metabolic marker in the blood of individuals exposed to air pollution is plausible as some environmental pollutants have been observed to enter the blood stream directly from lungs. The main objective of the current review is to find out changes in biochemical parameters of human blood as a result of environmental pollution. Spatio temporal models involving measurement of  Air Quality Index were accommodating to find out the results of development of an aggregate air quality index. Results depicted that mean values of RBC and hemoglobin concentration in blood of exposed children were significantly different from those of non-exposed group. Air pollution may adversely affect children's erythrocytes, particularly PM10 have a significant negative relationship with hemoglobin and RBC numbers while a positive significant relationship with WBC and platelet count. Higher concentrations of air pollutants exposed to pregnant women significantly higher the incidence of pregnancy anemia’s. A strong dose-response relationship was confirmed for both contaminants. It is difficult to establish a causal relationship between specific environmental exposures and complicated multifactorial health outcomes, the application of non-targeted metabolite profiling to assess the effect of air pollution on blood metabolite. Therefore in the present study the main emphasis has been made on the effects of various polluted environment contaminants, their biochemical effects on the composition of blood and various associated disease.