The Arylnaphthalene Lactones Tale: Two NMR Spectroscopy Case Studies on the Surprises of a Dehydro-Diels−Alder Reaction

While case studies have found extensive uses in many disciplines, they are still lacking in chemistry. This paper aims to introduce two NMR spectroscopy case studies, an opportunity to showcase that chemistry could be taught using this format. Starting from simple isomeric molecules and their full spectroscopic analyses, students will be asked to unequivocally identify their structures as well as label all the spectra provided, all while being exposed to the intricacies of solving a problem set compiled in a case study format.