Pierre Robin Syndrome
2020
Pierre Robin sequence (PRS) is characterized by the clinical triad of micrognathia (mandibular hypoplasia), glossoptosis (downward displacement of the tongue), and upper airway obstruction. Clinically, this results in a small, underdeveloped mandible that causes the base of the tongue to fall back into the throat and can ultimately lead to upper airway compromise. It is commonly associated with cleft palate. These findings may be part of a syndrome or isolated. The sequence was first described in 1891. However, Pierre Robin first published a case of an infant with these characteristics in 1923.
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