Effects of Nonstarch Polysaccharides with Different Molecular Weights on the Development of Lewis Lung Carcinoma in Mice and Efficiency of Cytostatic Therapy

The effects of nonstarch polysaccharides with different molecular weights on the development of Lewis’ lung carcinoma and effi ciency of cyclophosphamide therapy in mice were studied. Treatment with these substances with low molecular weights ( 400 kDa) inhibited the growth of Lewis’ lung carcinoma node. Antimetastatic effects of cyclophosphamide were stimulated by low and high molecular weight polysaccharides.