UTILISATION D’IMPLANTS SOUS-CUTANÉS D’AGONISTES DE LA GNRH CHEZ LES CARNIVORES DOMESTIQUES POUR MAÎTRISER LA REPRODUCTION

The recent commercialisation in Europe of sub-cutaneous implants containing an agonist of the hypothalamic hormone GnRH, called deslorelin, has been done in the purpose of offering a chemical alternative to surgical castration in the adult male dog. The efficacy of these implants in this indication is real. They have an action on the endocrine function ( spectacular diminution of testosteronemia), on the exocrine function (alteration of sperm quality and infertility) and on the clinical evolution ( diminution of the size of the testis). The availability of these implants also gave rise to numerous other indications in the canine and feline species. Many recent publications, or even unpublished studies still going on, seem to show an interest in the improvement of unpleasant behavior potentially linked with testosterone in the male, but also to prevent fertility in the adult male cat and to prevent oestrus in the bitch or in the queen. Implantation of pre-pubertal animals to postpone puberty seems successful. In the adult bitch, induction of a fertile oestrus post-implantation is even possible, which bears a zootechnical interest. However, secondary effects, duration of action and further fertility after implantation are not well known at the moment and need to be further studied