therapeutic agents glyoxylate aminotransferase alanine

therapeutic agent AGXT I340M for use as a medicament, wherein the therapeutic agent AGXT I340M esseleccionado the group consisting of: a) a AGXT I340M protein comprising an amino acid sequence with at least 90% identity desecuencia with SEQ ID NO: 2 when aligned optimally over its entire length using the GAP program, where establishedpublic AGXT I340M protein comprises a methionine at a position corresponding to position 340 in SEQ ID position: 2; b) a nucleic acid molecule comprising a nucleotide sequence encoding a protein AGXT I340M taly as defined in a); and, c) a vector virion viral gene therapy comprising a nucleic acid molecule as defined ENB).