CYCLIC STRETCHING OF ANTERIOR CRUCIATE LIGAMENT-DERIVED FIBROBLASTS IN 2D AND 3D BIOMATERIAL-FREE AND BIOMATERIAL CULTURES LEADS TO SYNCHRONIZED CELL ORIENTATION AND ACTIVATION

Ligament fibroblasts must be mechanosensitive and possess sufficient adaptability to a novel mechanomilieu ensuring the permanent load capacity of the tissue. Once mechanoreceptors are activated, t...