Phenome Centers and Global Harmonization

Phenomics, which is the study of how human genes interact with its environment, offers a unique perspective through which physicians and scientists alike can understand underlying disease processes. The detection and measurement of metabolites, which are the cellular end products, provide a holistic view of how particular treatments and interventions modulate cellular function and output. Phenome centers explore this at population and patient levels to detect metabolic biomarkers of disease. These markers can then be used to inform clinical decision making at the patient level. The technologic platforms that include sophisticated computational power bridge an important gap to better customize health care solutions for patients. Phenome centers serve a pivotal role in linking metabolic data with patient-level genomic, proteomic, and image data, which will better serve to optimize the patterns of care and improve patient outcomes and resource utilization.